Learn as Vy Dong gives the 2023 Distinguished Lectures covering metal hydrides, which promote a wide-range of organic transformations that include both C-C bond making and C-C bond breaking processes.

These three lectures will highlight the development of transition-metal catalysts for use in enantioselective hydrofunctionalizations (e.g., hydroacylation, hydroamination, and hydrothiolation). In addition, a unique transfer hydroformylation will be described that allows conversion of aldehydes/alcohols to olefins. The presentation emphasizes mechanistic studies that showcase the role of counter-ions for controlling selectivities. Lastly, we disclose applications of these catalysts for transforming feedstocks into more complex building blocks and natural products.