Todd Hyster, Princeton University, "Photoenzymatic Catalysis - Using Light to Reveal New Enzyme Functions.". Preparing molecules of interest via new catalyst design is a defining feature of modern organic chemistry. Despite tremendous advances, classical approaches such as organocatalysis and transition metal catalysis have difficulty addressing synthetic challenges. Our research group is interested in exploiting protein-based catalysts to address these challenges. These solutions range from developing new protein/catalysts hybrid complexes to engineering existing enzyme complexes to catalyze new, synthetically interesting reactions.
The aim of these new transformations will, in part, focus on the synthesis of nitrogen containing molecules. Basic nitrogen is found in the vast majority of medicinally and biologically relevant targets. The ability to access new types of nitrogen containing molecules can potentially lead to the discovery of new biological entities.
Friday, January 31 at 9:00am
Hutchison Hall, 473
Hutchison Hall, Rochester, NY