Presentation 2:  Mitochondrial Stress and Adaptation, presented by Keith Nehrke, PhD, Professor of Medicine, Department of Medicine, Division of Nephrology, URMC.  

Educational Objectives:

At the conclusion of Presentation 1 participants should be able to:

1.  Describe a possible mechanism for why patients with POMC or MC4R deficiency do not exhibit fasting hyperglycemia or impaired glucose tolerance despite insulin resistance.

2.  Explain the pathway through which the brain controls glucose reabsorption.

At the conclusion of Presentation 2 participants should be able to:

1.  Describe how mitochondria coordinate stress responses with the nuclear genome.

2.  Understand the relevance of mitochondrial stress to ischemia-reperfusion injury.

Certification:

The University of Rochester School of Medicine and Dentistry designates this live educational activity for a maximum of 1 AMA PRA Category 1 Credit(s)^TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.