Benjamin Frisch, Ph.D., Research Assistant Professor in the Department of Medicine, Hematology/Oncology, will present “The Chemokine CCL3 in the Leukemic Microenvironment.”
Seminar Abstract: Hematologic malignancies are a group of diseases that are primarily associated with the bone marrow. As such, interaction with the bone marrow microenvironment represents a shared feature of leukemias with the potential to be targeted for therapy. My research has focused on the consequences for hematopoietic function and leukemic progression that result from increased inflammatory mediators in the marrow during hematologic malignancy. Using murine models and patient samples of myelogenous leukemias the chemokine CCL3 has been identified as a major factor in the bone marrow microenvironmental dysfunction, and a potential therapeutic target.
Monday, December 10, 2018 at 12:00pm to 1:00pm
School of Medicine and Dentistry, Upper Auditorium 3-7619
415 Elmwood Ave, Rochester, NY 14642