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Early Life Adversity and Adolescent Development: A Focus on Brain Development and Substance Use

Caregiving deprivation and maltreatment during childhood have impacts on adolescent development, including neural and behavioral development. This talk will review what has been discovered in research examining the impact of institutional orphanage care and child maltreatment on brain development and the development of substance use and disorder.  These findings will then be discussed in the context of adolescence and how this developmental period is a crucial time of risk and opportunity following early-life adversity.

Elizabeth Handley, Ph.D., Director of Research at Mt. Hope Family Center and an Assistant Professor at the University of Rochester

Mac Herzberg, Ph.D., a post-doctoral research scholar in the Department of Psychiatry at Washington University School of Medicine in St. Louis

The TRANSFORM Center is a unique partnership between the University of Rochester (UR) and the University of Minnesota (UMN) with support from the Educational Development Center, Inc. TRANSFORM research is jointly conducted at the UR’s Mt. Hope Family Center and UMN’s Institute for Translational Research in Children’s Mental Health. The TRANSFORM Community Engagement Core (CEC) is housed at UR’s School of Medicine and Dentistry in the Department of Psychiatry,  the Laboratory of Interpersonal Violence and Victimization (LIVV), and the Susan B. Anthony Center.

Thursday, June 24 at 12:00pm to 1:00pm

Virtual Event
Event Type

Lectures and Talks


Faculty, Students, Staff, Health Care Professionals



Department of Psychiatry, Susan B. Anthony Center
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