Highlighting clinical, translational, and data science research within the recently combined Aab Cardiovascular Research Institute (CVRI)/Clinical Cardiovascular Research Center (CCRC).

This all-day event will feature invited speakers, short talks, a poster session, and a keynote address by Kory Lavine, MD, PhD, director of the Center for Cardiovascular Research at WashU Medicine, titled "New Approaches to Repair the Failing Heart."

Please register to attend. You may also submit 250-word abstracts to present posters or short talks at the registration link. 

Agenda

8:30 – 9:00 a.m.         Pre-meeting coffee

9:00 – 9:30 a.m.         Welcome and introduction to the newly merged CVRI/CCRC Institute

Innovative Translational Research Presentations (20 min talks, 5 min questions)

9:30 – 9:55 a.m.         Doug Anderson, PhD – StitchR and CirculR: From RNA stitching technologies to therapeutics

9:55 – 10:20 a.m.       Wojciech Zareba, MD, PhD – Currently ongoing gene therapy clinical trials for cardiovascular diseases

Basic/Clinical Short Presentations Chosen from Abstracts (10 min talks, 5 min questions)

10:20 - 10:40 a.m.      Vivian Chen, PhD, Postdoc – Unveiling the novel therapeutic role of PDE10A-mediated functional protein complex in cardiac Hypertrophy

10:40 – 10:55 a.m.     Jessica Perciaccante, Graduate Student – CARDINAL functions as an RNA co-regulator of SRF-dependent gene transcription by co-occupying SRF-bound gene promoters in the heart

11:00 – 12:00 p.m.     Keynote Lecture: Kory Lavine, MD, PhD, Washington University - New Approaches to Repair the Failing Heart.

12:00 – 1:30 p.m.                               POSTER SESSION and LUNCH    

Innovative Translational Research Presentations (20 min talks, 5 min questions)

1:30 – 1:55 p.m.         Eric Small, PhD – Using transcriptomics and AI in translational cardiac fibrosis research

1:55 – 2:20 p.m.         Ilan Goldenberg MD – Cardiovascular research databases: The new horizon to enable AI and big data research

2:20 – 2:45 p.m.         Alex Nakonechnyi PhD – Innovative AI-driven cardiovascular research

Short Talks Chosen from Abstracts (10 min talks, 5 min questions)

2:45 - 3:00 p.m.          Preeti Mauyra, PhD, Staff Scientist – Neonatal platelets induce monocytes to a myeloid-derived suppressor cell phenotype – transfusion implications

3:00 – 3:15 p.m.         Justin Ryan, PhD, Research Assistant Professor, SUNY Upstate – Risk of arrhythmias in people with post-traumatic epilepsy

3:15 – 3:30 p.m.         Shumin Wang, PhD, Staff Scientist – Monocyte-derived delta-like 4 contributes to systemic inflammation in people living with HIV 

3:30 – 3:45 p.m.         Xiaoyi Liu, Graduate Student – Control of fibroblast proliferation and fibrosis by tumor suppressors

3:45 – 4:00 p.m.         Lindsey Wainwright, Graduate Student – RNA aptamers for RNA drug delivery in cardiac cells

4:00 – 5:00 p.m.         Post-symposium drinks and networking